다음에 대한 결과:
spy
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Hi All,
I'm attempting to put a set of simbiology global sensitivity analysis plots into my thesis and I'm running into some issues with the GSA plots. Firstly, the figures are very large, it would be quite beneficial to grab a set of the plots and arrange them myself, is there any documentation on how to mess around with the '1x1 Sobol' produced by sbiosobol? Or just GSA plots in general.
The second problem is that the results appear to be relative to the most sensitive parameter in that run. Is it recommended to have a resonably sensitive 'baseline' parameter in each run? I find it difficult to compare plots when a not so sensitive parameter is being recorded as near '1' for the whole run because it's being stacked against a set of very insensitive parameters. I.e. if i have multiple sets of GSAs due to a large model, how can I easily compare results? If I could do some single run through with every parameter that would be the ideal, I imagine, but then the default plot would be half a mile off the bottom of my screen, haha! Perhaps there is a solution to the first question that might help there?
Thank you for your help,
Dan
Hi all,
I've translated a model from another piece of software (monolix) into simbio programmatically to make use of your very easy global sensitivity analysis system.
It looks a little something like this, for a 'single' line example:
r1 = addreaction(model,'InsI -> InsP');
r1.ReactionRate = 'InsI*kip/vi'; %- is + panc
k1 = addkineticlaw(r1, 'Unknown');
Multiplied about 20 fold, as you can see I have included my volumes within the reaction rates myself (vi). The model functions perfectly and I have corrected the outputs at the end:
[time, x, names] = sbiosimulate(model,csObj,dObj1);
x(:,1) = x(:,1)/vi;
So that they are in concentration, as needed. However, when it comes to sensitivity analysis because I have corrected them post-model it is technically incorrect, it is analysing the absolute quantities. This is quite noticible in the sensitivity to the volumes.
Is there an easy fix to this, I've had to fight dimensionality with units in the past using simbio and I'd be great if there was some way of dividing a compartment output by a volume, for example. It is a functionality that exists in monolix, so I was hopeful it might here!
Thank you for your time.
EDIT:
I think I've worked it out, I had to refactor my model to operate in concentrations, just refitting it now. Now I should just be able to use unitless compartments.
I am trying to simulate model of blood lymphocyte count from a paper using Simbiology. The rate of in or out following circadian rythym is kp(t)=km + kb cos [(t-tpeak)*2pi/24] Where and how do I write the expression ? I dont think I can write in repeated assignment ?
I am currently facing a compatibility issue when attempting to load a SimBiology model created in MATLAB 2021a into MATLAB 2023a. Specifically, the code capture functionality does not seem to be working.
If anyone has encountered a similar situation or has insights on how to capture the code for a SimBiology model created in an older version of MATLAB, I would greatly appreciate your guidance. Are there any alternative methods or specific steps that can be followed to ensure successful code capture?
Thank you in advance for your time and expertise.
This is the 6th installment of the wish-list and bug report thread.
This topic is the follow on to the first Wish-list for MATLAB Answer sections and second MATLAB Answers Wish-list #2 (and bug reports). The third started out as New design of the forum - grey on white and the fourth and fifth also grew so large they are slow to load and navigate.
Same idea as the previous ones: one wish (or bug report) per answer, so that people can vote their wishes.
What should you post where?
Next Gen threads (#1): features that would break compatibility with previous versions, but would be nice to have
@anyone posting a new thread when the last one gets too large (about 50 answers seems a reasonable limit per thread), please update this list in all last threads. (if you don't have editing privileges, just post a comment asking someone to do the edit)
Dear community,
I would like to develop a fermentation model with 4 ODEs, one of which contains variable y. A "repeated assignment", e. g. y=5x+5, contains variable x that has been measured each second. These data (columns with time and corresponding value x in each row) are recorded in the Excel file.
Does anyone have any suggestion how to implement this in symbiology?
Thank you very much in advance,
Tetiana
Hi,
I want to develop a PK model based on some PK data. The PK data seems to display 2 peaks when one initial dose is given.
I would like to give one dose. A fraction of this dose (fr) is absorbed following the linear relationship - ka*Drug the other fraction (1-fr) is absorbed following a linear absorption (ka1*Drug) with a Tlag (it maybe a zero order). The fraction fr is unknown so it must be estimate.
Does anyone have can provide any suggestion to implement this in symbiology or provide a link where I can look?
Thank you very much in advance,
Ferran
I have a species which is absorbed in a zero-order manner. I want to model the reaction rate as "UptakeRate*ActiveState". So I can give value of 1 or 0 to ActivateState to control the active state of this process. The species itself is under control multiple processes, so I want to use Event to automatically change the active state of absorption.
However, when I use these two events:
Event 1，trigger: species > 0, Function: ActiveState =1; Event 2, trigger: species <=0, Function: ActiveState=0
The simulation seems to be stuck without stop.
Is there any way to solve this ? Thanks
Hi,
Im a new user of simbiology, can any one tell me How to fix a parameters to a known constant when estimating models.
Hello,
In the previous versions, we were able to change the reaction line properties to Reactant, Product, or Reactant and Product. This option is not available in 2021b. How do we change the proerpties if we reaction line is both Reactant and Product?
Thanks
Simulations and model results do not get exported to the MATLAB workspace automatically. 2021b. Under Model Analyzer preferences, I checked "export results when model run is complete", but to no effect. I have to manually expert simulations after each run. Please advise. Thanks RD
This is not a question, but a point of discussion for the entire community. I am aware that every 1/2 months this theme comes out, but until this is not fixed it is totally necessary that this comes, indeed, out. And I said "fix" because Mathworks has to understand that a dark theme is not only a visual/aesthetic matter, it is a substantial part of the game. Most of the OS, GUIs, programs are actually in dark mode, and a vast majority of the users makes indeed use of a global dark mode. How much one does like it is personal, but the benefits to power savings and eye health is instead a fact. Mathworks being ignoring this for years is nothing but ridiculous. Of course it is not an easy task, but every minute of committment for it is worthy. And nope, Schemer is not helpful because it does not provide a real fix to this question.
I feel free to suggest something similar to the Spyder's dark theme, which came out like 2 years ago if I remember correctly.
Of course, my point is not being disrespectful (I am instead very respectful to the huge efforts of Mathworks for making this wonderful program run). But, form a user's point of view, the fact that not a single word has so far come out from Mathworks about a dark theme (meaning that for sure we will not see it in a timing of months) requires us to put a strong pressure on this.
Mathworks, please: it's time for a dark theme.
Let's say MathWorks decides to create a MATLAB X release, which takes a big one-time breaking change that abandons back-compatibility and creates a more modern MATLAB language, ditching the unfortunate stuff that's around for historical reasons. What would you like to see in it?
I'm thinking stuff like syntax and semantics tweaks, changes to function behavior and interfaces in the standard library and Toolboxes, and so on.
(The "X" is for major version 10, like in "OS X". Matlab is still on version 9.x even though we use "R20xxa" release names now.)
What should you post where?
Next Gen threads (#1): features that would break compatibility with previous versions, but would be nice to have
@anyone posting a new thread when the last one gets too large (about 50 answers seems a reasonable limit per thread), please update this list in all last threads. (if you don't have editing privileges, just post a comment asking someone to do the edit)
Hello
I would like to pulse an input species. I read in the forums that repeated assignments can be used for this, but I am not exactly sure how to implement this. This is the MATLAB code that resembles what I would like the input pattern to be:
t = 0:1/1e3:60; d = [10:2:30]'; x = @rectpuls; y = pulstran(t,d,x);
plot(t,y)
hold off
xlabel('Time (s)')
ylabel('Waveform')
Thanks for any help! Aaron
Hello, We would like to share one of our QSP models with non-modeler colleagues for them to play with. Is there a simple way to generate a standalone app from a SimBiology model, with sliders allowing the user to change various parameter values?
Thank you,
Abed
Is anyone else disappointed with uifigures? It seems apparent that these will eventually replace traditional figures, but there is still so much that doesn't quite work. I've tinkered with uifigures since their introduction in release 2016a, but even in 2020a I can't reliably export a uifigure to a graphics file. Sure it works sometimes, but not if a uipanel is present. The exportgraphics command is not as powerful as the print command, leaving some graphic formats (such as *.svg and *.eps) unsupported. How do you generate graphic files of a specific size? You can't even use subplots without overriding the default AutoResizeChildren setting!
Everything with uifigures seems to be slower and less stable than the figure variant. App Designer is much better than GUIDE, but that is not exactly high praise. I would rather generate "apps" programatically across several files instead of dealing with a single-file class definition containing 1000+ lines.
Where is this transition going? MATLAB graphics are moving away from Java in favor of JavaScript, and I'm not sure that we are at all ready for that.
Hello, Does the 'sbiofit' function have functionality implemented for likelihood=based handling of BLoQ censored data, similar to functionality in NONMEM and other softwares? If not, are there plans to implement this?
Thanks,
Abed
Hello,
I recently downloaded the GlobalSensitivityAnalysisApp. I am trying to perform a GSA using a simbiology model. I try running the App, but I get the error "No Sobol Indices Available to Plot. Configure the Sobol section and click the Compute button." I'm not sure if there is a step I'm overlooking. I'm following the instructional video for this app on the Matlab website, and I'm not sure what Configure the Sobol section is referring to. Any guidance would be greatly appreciated.
