Target-Mediated Drug Disposition
Generic Target-Mediated Drug Disposition (TMDD) model that accounts for saturable drug-target binding, as well as target mediated elimination.
Model of the systemic Renin-Angiotensin-System (RAS) to investigate the effects of different RAS-modulating therapies.
Physiologically-based pharmacokinetics of trichloroethylene
Physiologically based: Human PBPK model for trichloroethylene (TCE) and its metabolites to assess human health risks associated with low level exposure to TCE.
A gathering place for scientists working in QSP, PBPK, and PK/PD modeling using SimBiology and MATLAB. Features discussions, shared models and code, and other resources from our global community of users.