SimBiology Tutorials for QSP, PBPK, and PK/PD Modeling and Analysis

SimBiology provides apps and programmatic tools to model, simulate, and analyze dynamic systems, focusing on quantitative systems pharmacology (QSP), physiologically-based pharmacokinetics (PBPK), and pharmacokinetics/pharmacodynamics (PK/PD) applications. The videos in this series walk you through how to use SimBiology and perform common tasks.

SimBiology Tutorials: Getting Started with SimBiology Get an overview of the SimBiology app layout and navigation.

SimBiology Tutorials: Building a Model – Differential Equations Learn how to define differential equations with SimBiology using the Model Builder app.

SimBiology Tutorials: Building a Model – Algebraic Equations Learn how to define algebraic equations with SimBiology of the Model Builder app.

SimBiology Tutorials: Simulating a Model in SimBiology This video demonstrates how to simulate a model in SimBiology in the SimBiology Model Analyzer App.

SimBiology Tutorials: Working with Doses in SimBiology Create and apply dose schedules to a model in SimBiology .

SimBiology Tutorials: Stratifying Data for Visualization in SimBiology Learn how to use the Model Analyzer app in SimBiology to easily slice or stratify your experimental data and visualize simulation results.

SimBiology Tutorials: Generating Simulation Scenarios by Sampling Model Quantities Learn how to sample model quantities such as parameters and initial concentrations, dosing schedules, and parameter variants.

SimBiology Tutorials: Importing Data and Noncompartmental Analysis Importing Data and Noncompartmental Analysis video: Import data from spreadsheets into SimBiology and perform noncompartmental analysis (NCA).

SimBiology Tutorials: Estimating Parameters (Fixed Effects) Estimating Parameters (Fixed Effects) video: Perform fixed effects parameter estimation, visualize fit results and compare multiple fits

SimBiology Tutorials: Estimating Parameters (Mixed Effects) Estimating Parameters (Mixed Effects) video: Perform mixed effects parameter estimation

SimBiology Tutorials: Sampling Parameters from Covariate Models in SimBiology Learn how to sample parameter values from covariate models in SimBiology.