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Simultaneous Fit of IV and PO data using SimBiology

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Engie Salama
Engie Salama 23 Jun 2020
댓글: Engie Salama 1 Jul 2020
Hello,
I was wondering if there was a way to model both IV and PO data simultaneously for the same patients using SimBiology; I've successfully fitted the IV data in one model and the PO data using the same model but with different initial estimates, but I was wondering if it's possible to do one fit for both datasets. I get an error when I try to do both because the time course for the IV data and the PO data uses the same scale (0-144 hours)
Thanks in advance!

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Arthur Goldsipe
Arthur Goldsipe 24 Jun 2020
Yes, it is possible to fit two model outputs at the same time. Do you want to do this using sbiofit or a fit program in the SimBiology Analysis app? Here's an example of a simultaneous fit to two different compartments.
I don't understand what you mean about getting an error because the data uses the same time scale. If you can share some more details (the exact error message and how to reproduce it), then we should be able to help you.
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Engie Salama
Engie Salama 1 Jul 2020
Excellent, thank you for your help Arthur :)

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