How do i applying GLM to imported Excel data for numerical and categorical data?

I have imported some data from Excel into Matlab. The heading of each row was not imported however in the workspace each column is represented by its heading.

One of the columns is the response variable (Y) and the other variables are the predictor variables(x1,x2,...x22).

I am trying to apply generalised linear modelling to predictive model. I am trying to find out which of the predictor variables have the biggest effect on the response variable. The response variable can either be 0 or 1. The other variables are a range of categorical and numerical values. How do I do this after importing data?