I need to work with image files having .svs files. These files can be viewed by using the imagescope software available in thehttp://www.aperio.com/default.asp site. These files use JPEG 2000 compression. These files are of sizes 400~800 MB. I am currently using version 2009a. I can't load the files in MATLAB. Could you please help me with a solution? Is the size is problem or the format?