Single sample RNAseq data analysis

I have one patient RNAseq sample, no normal sample and a few other patient samples. Is there a way in Matlab that allows me to analyze this type of data?

[Ive J]

What do you mean exactly by allows me to analyze? Do you want some differential expression analysis? Do you have bulk or is it single-cell data? I'm not sure you can do much with only 1 group unless you want to study the differentially expressed genes in subgroups (e.g. say your patients can be further divided into various groups based on the severity of some conditions or diseases, then you can compare subgroups). In either case, MATLAB is not a viable choice, check R packages and tutorials (e.g. using R DESeq2 package) which are well-suited for such purposes.