Trigger Simulink Calculation from MATLAB script

Hi Guys,

I am a systems integrator and i need to integrate a Simulink calculation with PI AF(Database). As of now, the database emits files in a specific csv format that are converted to a .mat file manually using a tool. I need to convert the csv file into a .mat file using a MATLAB script and I need to trigger the Simulink calculation as it is from

The block diagram in Simulink has got file blocks as input which read a specific file from the folder for the calculation. I want to write a script that takes in the csv file and generates a .mat file of the same name in the same folder(replicating the work of the tool). Once this is done, I need to trigger the Simulink calculation.

How can i achieve this is MATLAB ? I am completely new to MATLAB and Simulink and I have never worked on them before.

Thanks.