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dose dependence in simbiology model

조회 수: 1 (최근 30일)
Anne Smith
Anne Smith 2022년 1월 27일
답변: Arthur Goldsipe 2022년 1월 28일
I was wondering if anyone was aware of an example online of how to incorporate dose-dependent absorption in a simbiology model?
I am using the 2021a GUI.
Many thanks, Anne

답변 (1개)

Arthur Goldsipe
Arthur Goldsipe 2022년 1월 28일
I think the answer depends on how, mathematically, you want to model dose-dependent absorption. You can easily create various PK models in SimBiology, as described here. One of the options for this is to model elimination with Michaelis-Menten kinetics. This would create dose-dependent elimination.
If that doesn't meet you needs, please share more details about how (mathetmatically) you want to model dose-dependent absorption.
I hope that helps.
-Arthur

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