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sbiosimulate

Simulate SimBiology model

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Syntax

[time,x,names] = sbiosimulate(modelObj)
[time,x,names] = sbiosimulate(modelObj,csObj)
[time,x,names] = sbiosimulate(modelObj,dvObj)
[time,x,names] = sbiosimulate(modelObj,csObj,dvObj)
[time,x,names] = sbiosimulate(modelObj,csObj,variantObj,doseObj)
simDataObj = sbiosimulate(___)

Description

[time,x,names] = sbiosimulate(modelObj) returns simulation results in three outputs, time, vector of time samples, x, simulation data, and names, column labels of simulation data x. This function simulates the SimBiology® model modelObj while using the active configuration set along with its active doses and active variants if any.

example

[time,x,names] = sbiosimulate(modelObj,csObj) returns simulation results using the specified configset object csObj, any active variants, and any active doses. Any other configsets are ignored. If you set csObj to empty [], the function uses the active configset.

example

[time,x,names] = sbiosimulate(modelObj,dvObj) returns simulation results using doses or variants specified by dvObj and the active configset. dvObj can be one of the following:

If you set dvObj to empty [], the function uses the active configset, active variants, and active doses.

If you specify dvObj as variants, the function uses the specified variants and active doses. Any other variants are ignored.

If you specify dvObj as doses, the function uses the specified doses and active variants. Any other doses are ignored.

example

[time,x,names] = sbiosimulate(modelObj,csObj,dvObj) returns simulation results using a configset object csObj and dose, variant, or an array of doses or variants specified by dvObj.

If you set csObj to [], then the function uses the active configset object.

If you set dvObj to [], then the function uses no variants, but uses active doses.

If you specify dvObj as variants, the function uses the specified variants and active doses. Any other variants are ignored.

If you specify dvObj as doses, the function uses the specified doses and active variants. Any other doses are ignored.

example

[time,x,names] = sbiosimulate(modelObj,csObj,variantObj,doseObj) returns simulation results using a configset object csObj, variant object or variant array specified by variantObj, and dose object or dose array specified by doseObj.

If you set csObj to [], then the function uses the active configset object.

If you set variantObj to [], then the function uses no variants.

If you set doseObj to [], then the function uses no doses.

example

simDataObj = sbiosimulate(___) returns simulation results in a SimData object simDataObj using any of the input arguments in the preceding syntaxes.

example

Examples

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Open Live Script

Load a sample SimBiology model.

sbioloadproject radiodecay.sbproj

Change the simulation stop time to 15 seconds.

csObj = getconfigset(m1,'active');
set(csObj,'Stoptime',15);

Simulate the model and return outputs in an array.

[t,x,n] = sbiosimulate(m1);

Plot the simulated results for species x and z.

figure;
plot(t,x)
xlabel('Time')
ylabel('States')
title('States vs Time')
legend('species x','species z')

Figure contains an axes object. The axes object with title States vs Time, xlabel Time, ylabel States contains 2 objects of type line. These objects represent species x, species z.

You can also return the results to a SimData object.

simData = sbiosimulate(m1);

Plot the simulated results.

sbioplot(simData);

Figure contains an axes object. The axes object with title States versus Time, xlabel Time, ylabel States contains 2 objects of type line. These objects represent x, z.

Open Live Script

Load a sample SimBiology model.

sbioloadproject radiodecay.sbproj

Add two doses of 100 molecules each for species x, scheduled at 2 and 4 seconds respectively.

dObj1 = adddose(m1,'d1','schedule');
dObj1.Amount = 100;
dObj1.AmountUnits = 'molecule';
dObj1.TimeUnits = 'second';
dObj1.Time = 2;
dObj1.TargetName = 'unnamed.x';

dObj2 = adddose(m1,'d2','schedule');
dObj2.Amount = 100;
dObj2.AmountUnits = 'molecule';
dObj2.TimeUnits = 'second';
dObj2.Time = 4;
dObj2.TargetName = 'unnamed.x';

Simulate the model using no dose or any subset of the dose array.

sim1 = sbiosimulate(m1);
sim2 = sbiosimulate(m1,dObj1);
sim3 = sbiosimulate(m1,dObj2);
sim4 = sbiosimulate(m1,[dObj1,dObj2]);

Plot the results.

sbioplot(sim1);

Figure contains an axes object. The axes object with title States versus Time, xlabel Time, ylabel States contains 2 objects of type line. These objects represent x, z.

sbioplot(sim2);

Figure contains an axes object. The axes object with title States versus Time, xlabel Time, ylabel States contains 2 objects of type line. These objects represent x, z.

sbioplot(sim3);

Figure contains an axes object. The axes object with title States versus Time, xlabel Time, ylabel States contains 2 objects of type line. These objects represent x, z.

sbioplot(sim4);

Figure contains an axes object. The axes object with title States versus Time, xlabel Time, ylabel States contains 2 objects of type line. These objects represent x, z.

Open Live Script

Load a sample SimBiology model.

sbioloadproject radiodecay.sbproj

Create a new configset with a stop time of 15.

cs1 = addconfigset(m1,'cs1');
cs1.StopTime = 15;

Add a scheduled dose of 100 molecules at 2 seconds for species x.

dObj = adddose(m1,'d1','schedule');
dObj.Amount = 100;
dObj.AmountUnits = 'molecule';
dObj.TimeUnits = 'second';
dObj.Time = 2;
dObj.TargetName = 'unnamed.x';

Simulate the model using configset and dose objects.

sim = sbiosimulate(m1,cs1,dObj);

Plot the result.

sbioplot(sim);

Figure contains an axes object. The axes object with title States versus Time, xlabel Time, ylabel States contains 2 objects of type line. These objects represent x, z.

Open Live Script

Load a sample SimBiology model.

sbioloadproject radiodecay.sbproj

Add a new configuration set using a stop time of 15 seconds. 

csObj = m1.addconfigset('newStopTimeConfigSet');
csObj.StopTime = 15;

Add a scheduled dose of 100 molecules at 2 seconds for species x.

dObj = adddose(m1,'d1','schedule');
dObj.Amount = 100;
dObj.AmountUnits = 'molecule';
dObj.TimeUnits = 'second';
dObj.Time = 2;
dObj.TargetName = 'unnamed.x';

Add a variant of species x using a different initial amount of 500 molecules.

vObj = addvariant(m1,'v1');
addcontent(vObj,{'species','x','InitialAmount',500});

Simulate the model using the same configset, variant, and dose objects. Use the same order of input arguments as shown next.

sim = sbiosimulate(m1,csObj,vObj,dObj);

Plot the result.

sbioplot(sim);

Figure contains an axes object. The axes object with title States versus Time, xlabel Time, ylabel States contains 2 objects of type line. These objects represent x, z.

Input Arguments

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SimBiology model, specified as a SimBiology model object. The model minimally needs one reaction or rate rule for simulations.

Configuration set object, specified as a configset object that stores simulation-specific information. When you specify csObj as [], sbiosimulate uses the currently active configset object.

If your model contains events, the csObj object cannot specify 'expltau' or 'impltau' for the SolverType property.

If your model contains doses, the csObj object cannot specify 'ssa', 'expltau', or 'impltau' for the SolverType property.

Dose or variant object, specified as a ScheduleDose object , RepeatDose object , an array of dose objects, Variant object , or an array of variant objects.

  • Use [] when you want to explicitly exclude any variant objects from the sbiosimulate function.

  • When dvObj is a dose object, sbiosimulate uses the specified dose object as well as any active variant objects if available.

  • When dvObj is a variant object, sbiosimulate uses the specified variant object as well as any active dose objects if available.

Variant object, specified as a Variant object or an array of variant objects. Use [] when you want to explicitly exclude any variant objects from sbiosimulate.

Dose object, specified as a ScheduleDose object , RepeatDose object , or an array of dose objects. A dose object defines additions that are made to species amounts or parameter values. Use [] when you want to explicitly exclude any dose objects from sbiosimulate.

Output Arguments

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Vector of time samples, returned as an n-by-1 vector containing the simulation time steps. n is the number of time samples.

Simulation data, returned as an n-by-m data array, where n is the number of time samples and m is the number of states logged in the simulation. Each column of x describes the variation in the quantity of a species, compartment, or parameter over time.

Names of species, compartments, or parameters, returned as an m-by-1 cell array of character vectors. In other words, names contains the column labels of the simulation data, x. If the species are in multiple compartments, species names are qualified with the compartment name in the form compartmentName.speciesName.

Simulation data, returned as a SimData object that holds time and state data as well as metadata, such as the types and names for the logged states or the configuration set used during simulation. You can access time, data, and names stored in a SimData object by using its properties.

Version History

Introduced before R2006a

See Also

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