Four parameters logistic regression - There and back again

버전 2.0.0.0 (16.5 KB) 작성자: Giuseppe Cardillo
Fit data points with a four points logistic regression or interpolate data.
다운로드 수: 3.1K
업데이트 날짜: 2018/3/29

Four parameters logistic regression.
One big holes into MatLab cftool function is the absence of Logistic Functions. In particular, The Four Parameters Logistic Regression or 4PL nonlinear regression model is commonly used for curve-fitting analysis in bioassays or immunoassays such as ELISA, RIA, IRMA or dose-response curves. It is characterized by it’s classic “S” or sigmoidal shape that fits the bottom and top plateaus of the curve, the EC50, and the slope factor (Hill's slope). This curve is symmetrical around its inflection point. The 4PL equation is:
F(x) = D+(A-D)/(1+(x/C)^B)
where:
A = Minimum asymptote. In a bioassay where you have a standard curve, this can be thought of as the response value at 0 standard concentration.
B = Hill's slope. The Hill's slope refers to the steepness of the curve. It could either be positive or negative.

C = Inflection point. The inflection point is defined as the point on the curve where the curvature changes direction or signs. C is the concentration of analyte where y=(D-A)/2.

D = Maximum asymptote. In an bioassay where you have a standard curve, this can be thought of as the response value for infinite standard concentration.

In this submission there are 2 functions: L4P - to find the 4 parameters and to fit your data (as calibrators...); L4Pinv - to interpolate data of unknown samples onto calibrators curve.

Enjoy!

Created by Giuseppe Cardillo
giuseppe.cardillo-edta@poste.it

To cite this file, this would be an appropriate format: Cardillo G. (2012) Four parameters logistic regression - There and back again https://it.mathworks.com/matlabcentral/fileexchange/38122

인용 양식

Giuseppe Cardillo (2024). Four parameters logistic regression - There and back again (https://github.com/dnafinder/logistic4), GitHub. 검색됨 .

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버전 게시됨 릴리스 정보
2.0.0.0

inputparser; github link

1.1.0.0

I uploaded L5Pinv instead of L4Pinv

1.0.0.0

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이 GitHub 애드온의 문제를 보거나 보고하려면 GitHub 리포지토리로 가십시오.