MATLAB Answers

How to get rid of "Integration Tolerance Not Met"?

조회 수: 33(최근 30일)
Victoria Miller
Victoria Miller 6 Apr 2021
I'm trying to run a simulation of a repressilator in E. coli and get the error message above. How would you recommend I fix this issue? I have already tried messing with the simulation settings, but no luck. Thanks so much.

답변(1개)

Arthur Goldsipe
Arthur Goldsipe 6 Apr 2021
If you simulate from the command line, you should see a warning that infinite or NaN (not-a-number) values occur during the simulation. (In R2021a you should also see these warnings in the SimBiology Model Analyzer app.)
This typically indicates a modeling error. I suggest decreasing the simulation time to something shorter and inspecting the results to make sure they make sense. I see that the value of "LacI mRNA" becomes negative after the first time step. And if I look at the reactions involving this species, the reactions rates don't look physically meaningful to me: "LacI mRNA" is consumed even when its concentration is 0.

제품

커뮤니티

더 많은 답변 보기:  SimBiology Community

Community Treasure Hunt

Find the treasures in MATLAB Central and discover how the community can help you!

Start Hunting!

Translated by