How does SimBiology calculate the "lambda" in NCA?

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Seokuee Kim
Seokuee Kim 2018년 10월 16일
댓글: Seokuee Kim 2018년 10월 16일
I was wonder that How does SimBiology calculate the "lambda" in NCA?
When I use WinNonlin, I can choice the weighting option in linear regression (ex. unweighted, 1/y, 1/y^2).
Although SimBiology doesn't provide the weighting option, I think that Simbiology uses any one of above.
Thank you.

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Arthur Goldsipe
Arthur Goldsipe 2018년 10월 16일
Hi,
Currently (as of R2018b), SimBiology's NCA uses linear regression with all of the points weighted equally. I'm guessing that's what you would call "unweighted."
-Arthur

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